Skip to main content
Mast Cell Activation Syndrome (MCAS)

Medical cannabis treatments for mast cell activation syndrome (MCAS)

Mast cell activation syndrome (MCAS) is a complex condition caused by the release of chemical mediators from abnormal mast cells, leading to a range of symptoms. Medical cannabis may be prescribed to help manage some of these symptoms as part of a wider treatment plan.

As a CQC-regulated clinic, our world-class clinical team can assess whether prescribed medical cannabis could improve quality of life for MCAS patients.

30-year

2 in 3

patients with Postural Tachycardia Syndrome (PoTS) and Ehlers-Danlos syndrome (EDS) also show signs of MCAS

97%

of prescribed medical cannabis patients report experiencing an improved quality of life

Symptoms

Abdominal cramps

Breathlessness or wheezing

Fatigue

Feeling faint or fainting

Headache

Irritated eyes

Itching, hives or nettle rash (urticaria)

Nausea/vomiting

Rapid pulse (tachycardia)

Red skin (flushing)

Skin swelling that moves around the body

Variable blood pressure

If you’re experiencing any of these symptoms, it’s important to seek tailored advice from a medical professional. In severe cases, MCAS may also cause anaphylaxis, which will require immediate treatment.

Treatment options:

If you have gout, there are several treatment options available to help relieve symptoms during a flare-up and prevent further potential flares. These include:

H1 antihistamines (cetirizine, loratadine, fexofenadine)

H2 antihistamines (famotidine)

Leukotriene blockers (montelukast)

Low histamine diet

Mast cell stabilisers (sodium cromoglycate, ketotifen)

Prescribed medical cannabis treatments

<p>Check your eligibility (takes 30s) for gout medical cannabis (THC) treatment with Releaf</p>

Join our growing community of over 240,000 people

Whether you’re new to cannabis-based medicines, switching from another medical cannabis clinic, or self-medicating, we’ll put you back in control of your health.

Review thumbnail
Verified
Lukas' Journey

Condition Peripheral Neuropathy

Subscriber 2 years

Review thumbnail
Verified
Brandon's Journey

Condition Anxiety & Depression

Subscriber 2 years

Review thumbnail
Verified
John's Journey

Condition Depression

Subscriber 2 years

Review thumbnail
Verified
Amber's Journey

Condition Chronic Pain

Subscriber 3 years

Review thumbnail
Verified
James' Journey

Condition Restless Legs Syndrome

Subscriber 2 years

Review thumbnail
Verified
Darren's Journey

Condition Insomnia

Subscriber 2 years

Review thumbnail
Verified
Matthew's Journey

Condition Depression

Subscriber 2 years

Review thumbnail
Verified
Marlyse's Journey

Condition CRPS

Subscriber 2 years

Review thumbnail
Verified
Lou's Journey

Condition Adjunctive Cancer Care

Subscriber 2 years

Review thumbnail
Verified
Martin's Journey

Condition Ehlers-Danlos Syndrome

Subscriber 2 years

Review thumbnail
Verified
Matt's Journey

Condition Insomnia & Chronic Pain

Subscriber 2 years

Review thumbnail
Verified
Ollie's Journey

Condition ADHD

Subscriber 2 years

Review thumbnail
Verified
Carla's Journey

Condition Endometriosis

Subscriber 2 years

Review thumbnail
Verified
Josh's Journey

Condition Chronic Pain

Subscriber 2 years

Review thumbnail
Verified
Simon's Journey

Condition Low Back Pain

Subscriber 2 years

Review thumbnail
Verified
Kim's Journey

Condition Arthritis

Subscriber 2 years

Review thumbnail
Verified
Isabelle's Journey

Condition ADHD

Subscriber 2 years

Review thumbnail
Verified
Georgia's Journey

Condition Anxiety & ADHD

Subscriber 2 years

Review thumbnail
Verified
Ethan's Story

Condition Chronic Pain

Subscriber 2 years

Review thumbnail
Verified
Brandon's Journey

Condition Anxiety & Depression

Subscriber 2 years

Review thumbnail
Verified
Maxim’s Journey

Condition Chronic Pain

Subscriber 2 years

Review thumbnail
Verified
Chloe's Journey

Condition Endometriosis

Subscriber 2 years

Review thumbnail
Verified
Daisy's Journey

Condition PTSD

Subscriber 2 years

Review thumbnail
Verified
Jess' Journey

Condition Fibromyalgia

Subscriber 2 years

A word from our specialist

“Mast Cell Activation Syndrome (MCAS) can be a hugely unpredictable condition for patients to live with, as symptoms can flare up across multiple areas of the body with little warning. That uncertainty can have a significant impact on everyday life.

Because MCAS affects everyone differently and has highly variable symptoms, it can also be particularly difficult to diagnose, leaving many patients struggling to access the treatments they need, when they need them most.

A medical cannabis prescription may be worth looking at alongside existing conventional treatments, like antihistamines and mast cell stabilisers. While it won't be right for everyone, some patients report notable improvements in day-to-day symptom management.”

Dr. Alex Van Heerden

Dr Alex Van Heerden

Medical Director

<p>Check your eligibility (takes 30s) for gout medical cannabis (THC) treatment with Releaf</p>

Articles on Mast cell activation syndrome (mcas)

06. 09. 2023

Is medical cannabis effective in managing pain?

If you are looking for a complementary pain management solution to add to your existing treatment plan, you are anything but alone. Right here in the UK, around 34% of the population (that's close to 15.5 million people) are affected by chronic pain. Chronic pain is an unwelcome passenger on the journey for many patients living with long-term medical conditions, and is a common symptom of countless diseases and illnesses.

29. 09. 2023

A guide to medicinal cannabinoids for pain

With the introduction of medical cannabis here in the UK, patients are now able to access cannabis based medical products (CBMPs) in the treatment of pain. And while this is great news for many, the world of CBMPs can be daunting – especially when there are so many cannabinoids at play.

18. 09. 2024

Exploring the benefits of medical cannabis for sleep disorders

Sleep is an essential process that allows our bodies and minds to repair themselves and function effectively. Getting enough high-quality sleep is therefore vital for maintaining our overall physical and mental health. Yet, research shows that a significant portion of the population is not getting enough sleep - with many suffering from sleep disorders. We’re taking a look at how medical cannabis treatment could be beneficial in treating common sleep disorders from insomnia to sleep apnoea.